Anastrozole (Arimidex) works by decreasing the amount of estrogen. Anastrozole (Arimidex) dosage is 1 mg tablet per day, in same cases only 1/2 a tablet per day. For bodybuilders and strength athletes, Anastrozole (Arimidex) is used to minimize the aromatization of anabolic steroids, and to a lesser extent for it’s ability to raise testosterone levels in users. By reducing the amount of estrogen in a steroid user’s body he will be able to avoid estrogen related side effects such as water retention, gynocomastia, etc. Obviously this is something that users should be hoping to limit as much as possible. In addition to decreasing estrogen it has been demonstrated that anastrozole can also increase testosterone levels by up to 58%, along with also raising levels of lutenizing hormone. This is quite significant especially when one considers that Anastrozole (Arimidex) can be used in conjunction with other compounds during a user’s post cycle therapy to raise natural testosterone levels once administration of anabolics steroids is completed via the hypothalamic testicular pituitary axis.
Oftentimes, Anastrozole is compared to Nolvadex (tamoxifen nitrate) as these two drugs are purposely for the reduction of estrogenic activity in the body to halt or delay the progression of cancer. However, Anastrozole is reportedly a more effective drug in combating estrogen-related concerns. This is because as an aromatase inhibitor it blocks the aromatase enzyme, thereby preventing the production of estrogen. Nolvadex, on the other hand, only hinders the action and not the production of this hormone. This is why Anastrozole is considered as the second-line defense against breast cancer. For those male bodybuilders who use steroids, Anastrozole can be effective drug in combating excess estrogen. It is usually taken with Nolvadex to ensure estrogen-related side effects are avoided. If used with such drugs as Propecia (finasteride), it results to more ideal outcome.
With Anastrozole preventing estrogen production and with finasteride preventing testosterone conversion to DHT (dihydrotestosterone), you have an efficient duo in eliminating these hormones (estrogen and DHT) undesirable effects, as far as bodybuilding is concerned. Propecia is a specific inhibitor of the 5a-reductase, the enzyme responsible in testosterone conversion to DHT. Propecia reduces the serum concentration of DHT and thereby reduces unwanted androgenic effects like male pattern baldness. If the bodybuilder is using highly aromatizable steroids, such as testosterone, you can achieve impressive muscle gains with decreased possibility of water retention and gynecomastia if you stack it with Anastrozole and Propecia. The result is a more ripped and defined physique. It is wrong to think, however, that estrogen and its effects (particularly water and fat retention) are absolutely detrimental to bodybuilding. Remember that this hormone is also responsible for muscle strength and gains. Consequently, it minimizes the occurrence of injury as it improves the ability of muscle fibers to withstand contractile tension or stress.
Notice that one of the side effects of Anastrozole use is the likely occurrence of fractures, a major drawback of this drug. This is because when Anastrozole effectively blocks the formation of estrogen, it effectively blocks the benefits of this hormone as well. This is why many still decide for estrogen receptor antagonists like Nolvadex and Clomid because these drugs allow some estrogen activity in the body.
Daily dosage for males is from 0.5mg to 3mg. For women, a maximum dosage of 1mg per day is enough to combat estrogenic side effects. Because Anastrozole has a short active life, dosages are usually taken 2 to 6 times a day at equal intervals. During PCT, athletes normally start with higher dosage then implement a progressive decrease in dosage. The PCT protocol typically runs for seven to 14 days. In clinical studies, it has been observed that a daily dose of 1 mg of this drug results to more than 80% of estrogen suppression.
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